Publications

• Gogiraju R, Witzler C, Shahneh F, Hubert A, Renner L, Bochenek ML, Zifkos K, Becker C, Thati M, Schäfer K. Deletion of endothelial leptin receptors in mice promotes diet-induced obesity. Sci Rep. 2023 May 22
• Pallares Robles A, Ten Cate V, Lenz M, Schulz A, Prochaska JH, Rapp S, Koeck T, Leineweber K, Heitmeier S, Opitz CF, Held M, Espinola-Klein C, Lackner KJ, Münzel T, Konstantinides SV, Ten Cate-Hoek A, Ten Cate H, Wild PS. Unsupervised clustering of venous thromboembolism patients by clinical features at presentation identifies novel endotypes that improve prognostic stratification. Thromb Res. 2023 May
• Zhang P, Solari FA, Heemskerk JWM, Kuijpers MJE, Sickmann A, Walter U, Jurk K. Differential Regulation of GPVI-Induced Btk and Syk Activation by PKC, PKA and PP2A in Human Platelets. Int J Mol Sci. 2023 Apr
• Ten Cate V, Prochaska JH, Schulz A, Nagler M, Robles AP, Jurk K, Koeck T, Rapp S, Düber C, Münzel T, Konstantinides SV, Wild PS. Clinical profile and outcome of isolated pulmonary embolism: a systematic review and meta-analysis. EClinicalMedicine. 2023 Apr
• Akbalut C, Arisz R, Baaten C, Baildildinova G, Barakzie A, Bauersachs R, Ten Berg JM, van den Broek W, de Boer HC, Broker V, Buka R, Ten Cate H, Cate AT, De Luca C, De Simone I, Dignat-George F, Freson K, Gazzaniga G, van Gorp E, Habibi A, Henskens YMC, Iding AFJ, Khan A, Koenderink G, Konkoth A, Lacroix R, Lahiri T, Lam W, Lamerton R, Lorusso R, Luo Q, Maas C, McCarty OJT, van der Meijden P, Meijers J, Mohapatra A, Nevo N, Pallares Robles A, Poncelet P, Reinhardt C, Ruf W, Saraswat R, Schonichen C, Schutgens REG, Simioni P, Spada S, Spronk HMH, Tazhibayeva K, Thachil J, Vacik-Diaz R, Veninga A, Verhamme P, Visser C, Watson SP, Wenzel P, Willems R, Willers A, Zhang P, Zifkos K, van Zonneveld AJ. Blood coagulation and beyond: Position paper from the Fourth Maastricht Consensus Conference on Thrombosis. Thromb Haemost. 2023 Mar.
• Nagy M*, Robles AP*, Visser M, Koeck T, Ten Cate V, Ten Cate-Hoek AJ, Schwers S, Heitmeier S, Ten Cate H, Wild PS, Spronk HMH. Predictive value for increased activated factor XI activity in acute venous thromboembolism. J Thromb Haemost. 2023 Mar. *Co-first authorship
• Iding AFJ, Kremers BMM, Pallares Robles A, Ten Cate H, Cate AT. Residual venous obstruction as an indicator of clinical outcomes following deep vein thrombosis: a management study. Thromb Haemost. 2023 Mar.
• Iding AFJ*, Robles AP*, Ten Cate V, Ten Cate H, Wild PS, Ten Cate-Hoek AJ. Exploring phenotypes of deep vein thrombosis in relation to clinical outcomes beyond recurrence. J Thromb Haemost. 2023 Feb. *Co-first authorship
• Iding AFJ, Kremers BMM, Nagy M, Robles AP, Ten Cate H, Spronk HMH, Ten Cate-Hoek AJ. Translational insights into mechanisms underlying residual venous obstruction and the role of factor XI, P-selectin and GPVI in recurrent venous thromboembolism. Thromb Res. 2023 Jan.
• Baidildinova G, Ten Cate V, Nagler M, Panova-Noeva M, Rapp S, Köck T, Prochaska JH, Heitmeier S, Gerdes C, Schwers S, Konstantinides SV, Münzel T, Espinola-Klein C, Lackner KJ, Spronk HMN, Ten Cate H, van der Meijden PEJ, Leineweber K, Wild PS, Jurk K. Subtype-specific plasma signatures of platelet-related protein releasate in acute pulmonary embolism. Thromb Res. 2022 Dec.
• Luo Q, Wenzel P. Properdin (factor P) as a new target cleaved by factor XIa: Intrinsic coagulation at the crossroads with inflammation. Res Pract Thromb Haemost. 2022 Nov.
• Kremers BMM, Posma JN, Heitmeier S, Glunz J, Ten Cate H, Pallares Robles A, Daemen JHC, Ten Cate-Hoek AJ, Mees BME, Spronk HMH. Discovery of four plasmatic biomarkers potentially predicting cardiovascular outcome in peripheral artery disease. Sci Rep. 2022 Nov.
• Pallares Robles A, Ten Cate V, Schulz A, Prochaska JH, Rapp S, Koeck T, Panova-Noeva M, Heitmeier S, Schwers S, Leineweber K, Seyfarth HJ, Opitz CF, Spronk H, Espinola-Klein C, Lackner KJ, Münzel T, Andrade-Navarro MA, Konstantinides SV, Ten Cate H, Wild PS. Association of FXI activity with thrombo-inflammation, extracellular matrix, lipid metabolism and apoptosis in venous thrombosis. Sci Rep. 2022 Jun.
• Leberzammer J, Agten SM, Blanchet X, Duan R, Ippel H, Megens RTA, Schulz C, Aslani M, Duchene J, Döring Y, Jooss NJ, Zhang P, Brandl R, Stark K, Siess W, Jurk K, Heemskerk JWM, Hackeng TM, Mayo KH, Weber C, von Hundelshausen P. Targeting platelet-derived CXCL12 impedes arterial thrombosis. Blood. 2022 Apr.
• Spada S, Luke B, Danckwardt S. The Bidirectional Link Between RNA Cleavage and Polyadenylation and Genome Stability: Recent Insights From a Systematic Screen. Front Gen. 2022 Apr.
• Huang J, Zhang P, Solari FA, Sickmann A, Garcia A, Jurk K, Heemskerk JWM. Molecular Proteomics and Signalling of Human Platelets in Health and Disease. Int J Mol Sci. 2021 Sep.
• Zifkos K, Dubois C, Schäfer K. Extracellular Vesicles and Thrombosis: Update on the Clinical and Experimental Evidence. Int. J. Mol. Sci. 2021 Aug.
• van Gorp RH, Baaten CCFMJ, Habibi A, Jaminon AMG, Peeters FECM, Leenders P, Crijns HJGMC, Heemskerk JWM, Reutelingsperger CP, Spronk HM, Schurgers LJ. Vitamin K antagonist use induces calcification and atherosclerotic plaque progression resulting in increased hypercoagulability. Eur Heart J Open. 2021 Aug.
• Baidildinova G, Nagy M, Jurk K, Wild PS, ten Cate H, van der Meijden PEJ. Soluble platelet release factors as biomarkers for cardiovascular disease. Front Cardiovasc Med (Thrombosis). 2021 Jun.
• van Gorp RH, Dijkgraaf I, Bröker V, Bauwens M, Leenders P, Jennen D, Dweck MR, Bucerius J, Briedé JJ, van Ryn J, Brandenburg V, Mottaghy F, Spronk HM, Reutelingsperger CP, Schurgers LJ. Off-target effects of oral anticoagulants - vascular effects of vitamin K antagonist and non-vitamin K antagonist oral anticoagulant dabigatran etexilate. J Thromb Haemost. 2021 Mar.
• Konkoth A, Saraswat R, Dubrou C, Sabatier F, Leroyer AS, Lacroix R, Duchez AC, Dignat-George F. Multifaceted role of extracellular vesicles in atherosclerosis. Atherosclerosis. 2021 Feb.
• Ten Cate V, Prochaska JH, Schulz A, Koeck T, Pallares Robles A, Lenz M, Eggebrecht L, Rapp S, Panova-Noeva M, Ghofrani HA, Meyer FJ, Espinola-Klein C, Lackner KJ, Michal M, Schuster AK, Strauch K, Zink AM, Laux V, Heitmeier S, Konstantinides SV, Münzel T, Andrade-Navarro MA, Leineweber K, Wild PS. Protein expression profiling suggests relevance of noncanonical pathways in isolated pulmonary embolism. Blood. 2021 Feb.
• Makhoul S, Kumm E, Zhang P, Walter U, Jurk K. The Serine/Threonine Protein Phosphatase 2A (PP2A) Regulates Syk Activity in Human Platelets. Int J Mol Sci. 2020 Nov.
• Nourse J, Spada S, Danckwardt S. Emerging Roles of RNA 3'-end Cleavage and Polyadenylation in Pathogenesis, Diagnosis and Therapy of Human Disorders. Biomolecules. 2020 Jun.

Awards

• Anxhela Habibi: Young Investigator Award (Oral Presentation), 3rd TICARDIO Conference Marseille (2023)
• Vanessa Bröker: Young Investigator Award (Oral Presentation), 3rd TICARDIO Conference Marseille (2023)
• Rocío Vacik Díaz: Young Investigator Award (Oral Presentation), 3rd TICARDIO Conference Marseille (2023)
• Vanessa Bröker: CARIM HS-BAFTA Award for talented PhD candidates (2023)
• Konstantinos Zifkos: Early Career Travel Award, ISTH (2022)
• Alejandro Pallares Robles: Young Investigator Award (Poster), 3rd TICARDIO Training Maastricht (2022)
• Ronald Saraswat: Young Investigator Award (Poster), 3rd TICARDIO Training Maastricht(2022)
• Gaukhar Baidildinova: Young Investigator Award (Poster), 3rd TICARDIO Training Maastricht (2022)
• Claudia Schönichen: Early Career Travel Award, ISTH (2021)
• Gaukhar Baidildinova: Young Investigator Award (Oral Presentation + Poster), 5th European Spring School, Heraklion Greece (2021)